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Title: Phytochemical screening, antioxidant activity and in vitro biological evaluation of leave extracts of Hyptis suaveolens (L.) from south of Mexico
Authors: Sánchez Aguirre, Oscar
Cruz Navarro, Antonio
Guevara Valencia, Marina
Rengifo Salgado, Elsa Liliana
Vargas Arana, Gabriel
Keywords: Hyptis suaveolens
Plantas medicinales
Propiedades medicinales
Propiedades antimicrobianas
Compuestos fenólicos
Relajantes musculares
América Latina
Issue Date: Jan-2020
Publisher: Elsevier
Citation: South African Journal of Botany 128 : 62–66.
Abstract: Hyptis suaveolens (L.) is a medicinally plant available in the south and southeast region of Mexico, Latin America and the south and west region of Africa. Infusion of this plant is used to treat diarrhea and as a muscle relaxant. In this study the antioxidant and antibacterial activity, and the phenolic compounds content of Hyptis suaveolens leaves was evaluated. The antioxidant activity was performed by DPPH (1,1-diphenyl-2-picryl-hydrazyl) method, obtaining an IC50 range of 2.73–3.58 μg/mL for the different prepared extracts. The content of phenolic compounds was carried out by Folin-Ciocalteu method, obtaining for the extracts an oscillation of 253.68–336.50 mg of GAE/g of extract. The antibacterial activity was evaluated by disc diffusion method against Staphylococcus aureus, Escherichia coli and Salmonella thipy, of the three pathogenic microorganisms evaluated, S. aureus showed a higher sensitivity to treatment with a minimum inhibitory concentration (MIC) of 0.25 μg/mL, for E. coli and S. typhi was 0.5 μg/mL. The results confirm the great potential of this species as an antioxidant and antibacterial representing the first contribution to the chemical and biological knowledge of H. suaveolens from Mexican mountain range.
ISSN: 0254-6299
Appears in Collections:Artículos científicos en revistas indexadas

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